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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
TQ0091 | LY2795050 | Opioid Receptor | |
LY2795050 is a novel specific κ-Opioid Receptor antagonist (IC50: 0.72 nM). | |||
T16849 | SB-222200 | Neurokinin receptor | |
SB-222200 is a selective, reversible, and competitive antagonist of the human NK-3 receptor(Ki=4.4 nM). | |||
T6579 | Medetomidine hydrochloride | MPV785,Medetomidine HCl,Domitor | Adrenergic Receptor |
Medetomidine hydrochloride (MPV785) is a selective α2-adrenoceptor agonist, with Ki of 1.08 nM, exhibts 1620-fold selectivity over α1-adrenoceptor. | |||
T28352 | PDE9-IN-(S)-C33 | (S)-C33 | PDE |
PDE9-IN-(S)-C33 ((S)-C33) is a potent and selective inhibitor of PDE9 (IC50 = 11 nM). PDE9-IN-(S)-C33 can be used for central nervous system diseases and diabetes research. | |||
T19333 | Gadoteridol | ProHance,SQ-32692,Gd-HP-DO3A | Others |
Gadoteridol (Gd-HP-DO3A) is a gadolinium-based MRI contrast agent that can be used for central nervous system imaging. | |||
T23008L | MMPIP hydrochloride | MMPIP hydrochloride (479077-02-6 Free base) | GluR |
MMPIP hydrochloride is a selective antagonist of allosteric mGluR7. MMPIP hydrochloride can be used in research on the roles of mGluR7 on central nervous system functions. | |||
T0370 | Pheniramine maleate | Daneral,Inhiston,Trimetose | 5-HT Receptor , Histamine Receptor |
Pheniramine maleate (Trimetose), an alkylamine derivative with antihistaminic and vasodilatory properties, binds to histamine H1 receptors, thereby inhibiting phospholipase A2 and production of the endothelium-derived re... | |||
T68079 | Gedocarnil | ZK 113315,SH 530 | Others |
Gedocarnil(ZK 113315) may be used to study diseases of the central nervous system. | |||
T37089 | Iclepertin | BI-425809 | GlyT |
Iclepertin (BI-425809) is an orally active and selective inhibitor of glycine transporter protein 1 (GlyT1).Iclepertin is used for the treatment of central nervous system disorders such as Alzheimer;s disease. Iclepertin... | |||
T35009 | Vadocaine | Vadocaina,Vadocainum | Others |
Vadocaine (Vadocaina) is a novel analgesic compound for local anaesthesia and can be used to study the central nervous system and cardiovascular system. | |||
T27795 | Landipirdine | RO 5025181,RO5025181,SYN-120,SYN120,RO-5025181,SYN 120 | 5-HT Receptor |
Landipirdine (RO-5025181) is a selective 5-HT6R antagonist for the study of central nervous system disorders such as dementia. | |||
T7065 | Tizanidine | Adrenergic Receptor | |
Tizanidine, an α2-adrenergic receptor agonist, suppresses the release of neurotransmitters from central nervous system (CNS) noradrenergic neurons. | |||
T10881 | CPPHA | GluR | |
CPPHA, a positive allosteric modulator of glutamate receptors mGluR5 and mGluR1, is commonly used in development for central nervous system diseases. | |||
T10905 | CXCR2-IN-1 | CXCR | |
CXCR2-IN-1 has a pIC50 of 9.3 and is a CXCR2 antagonist of the central nervous system penetration agent. | |||
T6618 | Orphenadrine Citrate | Flexon,Flexoject,Banflex | AChR , iGluR |
Orphenadrine Citrate (Flexon) is a skeletal muscle relaxant, it acts in the central nervous system to produce its muscle relaxant effects. | |||
T27683 | JNJ-42253432 | P2X Receptor | |
JNJ-42253432 is an oral active P2X7 antagonist capable of penetrating the central nervous system with a pKi value of 9.1 for rat and 7.9 for human P2X7 channels. | |||
T7118 | Dimethocaine | Larocaine | Others , Dopamine Receptor |
Dimethocaine (Larocaine) is a local anesthetic which also effects on the central nervous system acting as dopamine-reuptake-inhibitor. | |||
T0702 | Gabapentin | Neurontin,Gabapentine,Aclonium | Calcium Channel , GABA Receptor |
Gabapentin (Neurontin) is an Anti-epileptic Agent. The physiologic effect of gabapentin is by means of Decreased Central Nervous System Disorganized Electrical Activity. | |||
T5422 | CID 1375606 | CID-1375606,CID1375606 | Others |
CID 1375606 is a surrogate agonist of orphan G protein-coupled receptor GPR27. characterized by a high level of conservation among vertebrates and a predominant expression in the central nervous system. | |||
T7433 | 2-Phenylethylamine hydrochloride | &beta,-Phenylethylamine hydrochloride,benzeneethanamine hydrochloride,&beta,-aminoethylbenzene hydrochloride | Others |
2-Phenylethylamine hydrochloride (benzeneethanamine hydrochloride) acts as neuromodulator in the central nervous system. It stimulates the release of norepinephrine and dopamine and is metabolized by monoamine oxidases a... | |||
T3659 | Zorifertinib | AZD3759 | EGFR |
Zorifertinib (AZD3759) is an orally active, effective and central nervous system-penetrant EGFR inhibitor. The IC50 values were 0.2, 0.3 and 0.2 nM for EGFR L858R mutant, TK wild-type, and Exon 19Del enzymes, respectivel... | |||
T1946 | Felbamate | W-554,ADD-03055 | NMDAR , iGluR |
Felbamate (W-554) is an Anti-epileptic Agent. The physiologic effect of felbamate is by means of Decreased Central Nervous System Disorganized Electrical Activity. | |||
T6649 | (S)-(+)-Rolipram | (S)-Rolipram,(+)-Rolipram,S- (+)-Rolipram | Apoptosis , PDE |
(S)-(+)-Rolipram ((+)-Rolipram) inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer. | |||
T50063 | (2-methyl-2,3-dihydro-1H-inden-2-yl)methanamine hydrochloride | Others | |
(2-methyl-2,3-dihydro-1H-inden-2-yl)methanamine hydrochloride is a cyclic amine that is structurally related to amphetamine and has been shown to have significant effects on the central nervous system. | |||
T32737 | Liafensine | BMS820836,BMS 820836,DB104,BMS-820836 | Dopamine Receptor , 5-HT Receptor , Norepinephrine |
Liafensine(BMS-820836) is a novel and selective triple monoamine reuptake inhibitor with inhibitory effects on the reuptake of serotonin, norepinephrine, and dopamine for the study of major depressive disorder and centra... | |||
T2196 | Fipronil | Fluocyanobenpyrazole,Termidor | P450 , GluCls , GABA Receptor |
Fipronil (Fluocyanobenpyrazole) is a broad-use insecticide that belongs to the phenylpyrazole chemical family. Fipronil is a broad-spectrum insecticide that disrupts the insect central nervous system by blocking GABA-gat... | |||
T6445 | Cilomilast | SB-207499,Ariflo | PDE |
Cilomilast (SB-207499) is a potent PDE4 inhibitor with IC50 of about 110 nM, has anti-inflammatory activity and low central nervous system activity. Phase 3. | |||
T1097 | Loratadine | SCH 29851,Loratidine | Influenza Virus , Histamine Receptor |
Loratadine (SCH 29851) is a second-generation histamine H1 receptor antagonist used in the treatment of allergic rhinitis and urticaria. Unlike most classical antihistamines (HISTAMINE H1 ANTAGONISTS) it lacks central ne... | |||
T2116 | AEE788 | NVP-AEE 788 | Apoptosis , EGFR , c-Fms , FLT , Bcr-Abl |
AEE788 (NVP-AEE 788) has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors. | |||
TP1442 | Neuromedin B | Endogenous Metabolite | |
Neuromedin B (NMB) is one of the bombesin (BN)-related peptides in mammals. It was originally purified from pig spinal cords, and it has been shown to be present in central nervous system as well as in gastrointestinal t... | |||
T0440 | Oxcarbazepine | GP 47680 | Apoptosis , Sodium Channel |
Oxcarbazepine (GP 47680) is an Anti-epileptic Agent. The physiologic effect of oxcarbazepine is by means of Decreased Central Nervous System Disorganized Electrical Activity. | |||
T2407 | Tiagabine | TGB,NO050328,Gabitril,NO328 | GABA Receptor |
Tiagabine (NO050328) is an Anti-epileptic Agent. The physiologic effect of tiagabine is by means of Decreased Central Nervous System Disorganized Electrical Activity. | |||
T13423 | (1R,2R)-2-PCCA hydrochloride | (1R,2R)-2-PCCA(hydrochloride) | Others |
(1R,2R)-2-PCCA hydrochloride is a potent, selective, and blood-brain-barrier-crossing GPR88 receptor agonist with an EC50 value of 1140 n in striatal membranes of WT mice.(1R,2R)-2-PCCA hydrochloride can be used to study... | |||
T14345 | Atropine methyl bromide | Methylatropine bromide | AChR |
Atropine methyl bromide (Methylatropine bromide) is a quaternary ammonium salt of atropine, characterized as a muscarinic receptor (mAChR) antagonist. It functions as a mydriatic to dilate the pupil during ophthalmic exa... | |||
T0680 | Lamotrigine | LTG,BW430C | 5-HT Receptor , Sodium Channel , Autophagy |
Lamotrigine (BW430C) is an Anti-epileptic Agent and Mood Stabilizer. The physiologic effect of lamotrigine is by means of Decreased Central Nervous System Disorganized Electrical Activity. | |||
T9687 | MAGL-IN-4 | His121 ARG57 | Lipase |
MAGL-IN-4 (His121 ARG57) is one of the monoacylglycerol lipase (MAGL) inhibitors in central nervous system-related diseases. | |||
T60712 | MAO-B-IN-17 | MAO | |
MAO-B-IN-17 is a selective and potent monoamine oxidase B (MAO-B) inhibitor (IC50: 5.08 μM) for the study of central nervous system disorders like Parkinson's. | |||
T19940 | Sulfoxaflor | GF 2372,GF 2032,XDE 208 | AChR |
Sulfoxaflor (GF 2032), an agonist of nAChR1 and nAChR2 subtypes, is a systemic insecticide that acts on the central nervous system of insects. Sulfoxaflor is used for the control of sap-feeding insects such as Nilaparvat... | |||
T30686 | Cafedrine | l-Cafedrine,Cafedrin | Others |
Cafedrine (Cafedrin) is found in tea and coffee and has a central nervous system stimulant effect.Cafedrine is often used in fixed 20:1 combination with cortisone in the study of acute hypotension.Cefetamet sodium (Cefet... | |||
T23016 | MRS1220 | MRS 1220 | Adenosine Receptor |
MRS1220, a selective and potent antagonist for the human A3 adenosine receptor (hA3AR) with a dissociation constant (Ki) of 0.59 nM, exhibits therapeutic promise for central nervous system disease research. It effectivel... | |||
T2191 | Tacrine hydrochloride (hydrate) | Tacrine,Tacrine hydrochloride hydrate,Tetrahydroaminacrine,Tetrahydroaminoacridine | AChR , AChE |
Tacrine hydrochloride hydrate (Tetrahydroaminacrine) is a cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and i... | |||
T77731 | ERK5-IN-6 | ERK | |
ERK5-IN-6 is a potent inhibitor of ERK5 kinase.ERK5-IN-6 exhibits antiproliferative activity, anticonvulsant activity, and antitumor activity, and can be used in the study of central nervous system-related disorders. | |||
T4249 | AZD3759 hydrochloride | EGFR | |
AZD3759 (hydrochloride) is an effective, orally active and central nervous system-penetrant EGFR inhibitor. At Km ATP concentrations, the IC50s are 0.2/0.3/0.2 nM for EGFR (L858R)/EGFR (wt)/EGFR (exon 19Del). | |||
TP1083L | Neuromedin U (rat) acetate | Others | |
Neuromedin U, rat acetate is a 23-amino acid brain-gut peptide. Neuromedin U (NMU), through its cognate receptor NMUR2 in the central nervous system, regulates several important physiological functions, including energy ... | |||
T1628 | Rivastigmine tartrate | SDZ-ENA 713,ENA 713 | AChR , AChE |
Rivastigmine tartrate (SDZ-ENA 713) is a carbamate-derived reversible CHOLINESTERASE INHIBITOR that is selective for the CENTRAL NERVOUS SYSTEM and is used for the treatment of DEMENTIA in ALZHEIMER DISEASE and PARKINSON... | |||
T1790 | Fosaprepitant dimeglumine | L785298,MK-0517,Fosaprepitant dimeglumine salt | Neurokinin receptor |
Fosaprepitant dimeglumine (MK-0517) is the dimeglumine salt form of fosaprepitant, the water-soluble, N-phosphorylated prodrug of aprepitant, with antiemetic activity. Upon intravenous administration and rapid conversion... | |||
T23097 | O-1602 | O1602,O 1602 | Cannabinoid Receptor , Calcium Channel |
O-1602 is a novel GPR55 agonist, an atypical cannabinoid associated with the central nervous system and obesity, and is a candidate compound for the treatment of cystitis.O-1602 promotes hepatic steatosis through GPR55 a... | |||
T26778 | Besipirdine | HP 749 free base,P-867493,P867493,HP 749,HP749,P 867493 | Sodium Channel , Adrenergic Receptor |
Besipirdine (HP 749 free base) is a non-receptor-dependent cholinomimetic compound with alpha-adrenergic and cardiovascular activities.Besipirdine inhibits voltage-dependent sodium-potassium channels and inhibits biogeni... | |||
T16115 | MLi-2 | LRRK2 | |
MLi-2 is a structurally novel, highly potent, and selective LRRK2 kinase inhibitor with central nervous system activity. MLi-2 exhibits exceptional potency in a purified LRRK2 kinase assay in vitro (IC50 = 0.76 nM), a ce... | |||
T2156 | WP1066 | Apoptosis , JAK , STAT | |
WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells; shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3. WP1066 has been used in trials studying the treatment of Melanoma, Bra... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T2S1464 | Thiocolchicoside | Thiocolchicine 2-glucoside analog,Coltramyl | Others , GABA Receptor |
Thiocolchicoside (Thiocolchicine 2-glucoside analog) (Muscoril, Myoril, Neoflax) is a muscle relaxant with anti-inflammatory and analgesic effects. It acts as a competitive GABAA receptor antagonist and also glycine rece... | |||
T0508 | γ-Aminobutyric acid | Gamma-aminobutyric acid,4-Aminobutyric acid,GABA,4-Aminobutanoic acid,Piperidic acid | GABA Receptor , Endogenous Metabolite |
γ-Aminobutyric acid (4-Aminobutyric acid) is the most common inhibitory neurotransmitter in the central nervous system. | |||
T1396 | Bemegride | Bemegrid,3-Ethyl-3-methylglutarimide,Agipnon | GABA Receptor |
Bemegride (3-Ethyl-3-methylglutarimide), a central nervous system stimulant, serves as an antidote for barbiturate poisoning. | |||
T6751 | Acetylcholine iodide | Acetylcolina | Others |
Acetylcholine iodide (Acetylcolina) is a neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the cent... | |||
T14046 | Anandamide | (5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide | Cannabinoid Receptor , Endogenous Metabolite |
Anandamide ((5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide), an immune modulator, acts via not only cannabinoid receptors (CB1 and CB2) but also other targets (e.g., GPR18/GPR55) in the central nervous sy... | |||
T1083 | Theophylline | Theo-24,1,3-Dimethylxanthine | Endogenous Metabolite , HDAC , PDE , Adenosine Receptor , Autophagy |
Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3... | |||
TN2322 | Yangambin | Calcium Channel , PAFR | |
Yangambin is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF); it has hypotensive effect, which is probably due to a peripheral vasodilatation that involves, at least, the inhibiti... | |||
T4A2458 | Resibufogenin | Bufogenin,Recibufogenin | Others |
1. Resibufogenin (Bufogenin) is a cytotoxic steroid isolated from the Chinese drug ChanSu. 2. Resibufogenin can inhibit rectifier potassium current ( I K ) and transient potassium current ( I A ), it has pathological eff... | |||
TN1516 | Cnidicin | NOS , NO Synthase | |
Cnidicin has anti-allergic and anti-inflammatory activity, it inhibits the degranulation of mast cell and the NO generation in RAW 264.7 cells(IC50 value, 7.5 microM). Cnidicin exhibits a significant inhibition on the pr... | |||
T6S1049 | Wilforine | ATPase | |
Wilforine is a sesquiterpene pyridine alkaloid; important bioactive compound in T. wilfordii plants, and is effective in treating idiopathic pulmonary fibrosis. Wilforine has anti-inflammatory effect, which might be medi... | |||
T15248 | Estetrol | Donesta | Estrogen Receptor/ERR , Endogenous Metabolite |
Estetrol(Donesta) is an orally available, selective modulator of the estrogen receptor, a naturally occurring estrogen synthesized by the human fetal liver during pregnancy.Estetrol has effects on the endometrium or cent... | |||
T0848 | L-DOPA | Levodopa,3,4-Dihydroxyphenylalanine | Dopamine Receptor , Endogenous Metabolite |
L-DOPA (Levodopa) is an amino acid precursor of dopamine with antiparkinsonian properties. Levodopa is a prodrug that is converted to dopamine by DOPA decarboxylase and can cross the blood-brain barrier. When in the brai... | |||
TN2240 | Strictosidinic acid | Others | |
Strictosidinic acid has an antiradical action against DPPH, it has a promising effect in the central nervous system. | |||
TMA0805 | Lupanine | ATPase , Potassium Channel , Calcium Channel | |
Lupanine has a weak sedative effect on the central nervous system, interaction with specific drugs used for treatment of the CNS and for analgesic activity. Lupanine improves glucose homeostasis by influencing KATP-chann... | |||
T35577 | Phosphatidylserines (bovine) | ||
Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. It is anionic and found mainly on th... | |||
T14011 | 2-Arachidonoylglycerol | Cannabinoid Receptor , Endogenous Metabolite | |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-05054 | Notch 4 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
NOTCH4 (Notch Receptor 4) is a Protein Coding gene. Notch4 belongs to a family of transmembrane receptors that play an important role in vascular development and maintenance. The NOTCH4 gene is located at 6p21.3 and is i... | |||
TMPY-03425 | Tau Protein, Human, Recombinant (His) | Human | E. coli |
MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are... | |||
TMPY-02525 | RGMA Protein, Human, Recombinant (His) | Human | HEK293 Cells |
RGMa, also known as RGM domain family, member A, belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein th... | |||
TMPJ-00651 | CD155/PVR Protein, Human, Recombinant (aa 21-343, His) | Human | HEK293 Cells |
Poliovirus Receptor (PVR) is a 70 kDa type I transmembrane single-span glycoprotein that belongs to the nectin-like (Necl) family and was originally identified based on its ability to mediate the cell attachment and entr... | |||
TMPJ-00562 | PDGF-BB Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (P... | |||
TMPY-01442 | DMBT1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB d... | |||
TMPJ-01065 | Noggin/NOG Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Noggin is a secreted homodimeric glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). Mouse Noggin cDNA encodes a 232 amino acid (aa) residue precursor protein with 19 aa residue putative signal pept... | |||
TMPY-01101 | Coagulation factor X/F10 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Coagulation factor X, also known as FX, F10, Eponym Stuart-Prower factor, and thrombokinase, is an enzyme of the coagulation cascade. It is one of the vitamin K-dependent serine proteases, and plays a crucial role in the... | |||
TMPH-02489 | ASCL2 Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. ASCL2 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression... | |||
TMPH-01722 | PLP1 Protein, Human, Recombinant (His) | Human | E. coli |
This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin. PLP1 Protein, Human, Recombinant (His) is expressed i... | |||
TMPH-02653 | FGF-20 Protein, Mouse, Recombinant | Mouse | E. coli |
Neurotrophic factor that regulates central nervous development and function. FGF-20 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 23.6 kDa and the accession numb... | |||
TMPH-02673 | GFAP Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. | |||
TMPY-00561 | Neurotensin Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
NTS (Neurotensin) is a Protein Coding gene. This gene encodes a common precursor for two peptides, neuromedin N and neurotensin. NTS is a neuropeptide distributed in the central nervous and digestive systems. It belongs ... | |||
TMPH-02674 | GFAP Protein, Mouse, Recombinant | Mouse | Baculovirus Insect Cells |
GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. | |||
TMPH-01504 | HAPLN2 Protein, Human, Recombinant (His) | Human | E. coli |
Mediates a firm binding of versican V2 to hyaluronic acid. May play a pivotal role in the formation of the hyaluronan-associated matrix in the central nervous system (CNS) which facilitates neuronal conduction and genera... | |||
TMPY-00286 | Neuropeptide Y Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
NPY (Neuropeptide Y) is a Protein Coding gene. This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress ... | |||
TMPJ-00846 | GFAP Protein, Human, Recombinant (His) | Human | E. coli |
Glial Fibrillary Acidic Protein (GFAP) is an intermediate filament (IF) protein which belongs to the intermediate filament family. GFAP is expressed in numerous cell types of the central nervous system (CNS), ependymal c... | |||
TMPK-01062 | RGMC Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
RGM gene family ('Repulsive Axonal Guidance molecules' A, B and C),both RGM A and B are mostly expressed in central nervous system, while RGM C is exclusively expressed in all striated muscle and in the myocardium. RGM A... | |||
TMPH-03292 | FGF-20 Protein, Rat, Recombinant (His & Myc) | Rat | E. coli |
Neurotrophic factor that regulates central nervous development and function. May play an important role in dopaminergic neurons in the substantia nigra. FGF-20 Protein, Rat, Recombinant (His & Myc) is expressed in E. col... | |||
TMPH-03756 | Wint7b Protein, Human, Recombinant (His & Myc & SUMO) | Human | E. coli |
Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta-catenin signaling pathway. Required for normal fusion of the chorion and the allantois during placenta d... | |||
TMPH-02861 | Wnt7b Protein, Mouse, Recombinant (His & Myc & SUMO) | Mouse | E. coli |
Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta-catenin signaling pathway. Required for normal fusion of the chorion and the allantois during placenta d... | |||
TMPJ-00295 | NgR Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Nogo Receptor (NgR) is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the Nogo recptor family. Human NgR is predominantly expressed in neurons and their axons in the central nervous systems. As a recept... | |||
TMPK-00861 | A2AR Protein-VLP, Human, Recombinant | Human | HEK293 Cells |
Adenosine is a neuromodulator in the adult central nervous system. Membrane-bound receptors for adenosine have been identified and cDNAs for A1, A2a, A2b, and A3 adenosine receptor subtypes have been cloned recently.Expr... | |||
TMPJ-00945 | HPCAL1 Protein, Human, Recombinant (His) | Human | E. coli |
Hippocalcin-Like Protein 1 (HPCAL1) is a neuron-specific calcium-binding member of the recoverin family which found in the retina and brain. HPCAL1 contains four EF-hand domains and it is highly similar to human hippocal... | |||
TMPY-01120 | VPAC2 Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
VIP and PACAP receptor 2, or VIPR2 encodes the VPAC2 receptor, which binds both VIP and PACAP. VPAC2 is expressed throughout the central nervous system and the periphery. Mutations in the VIPR2 homolog in the mouse cause... | |||
TMPK-00591 | RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (aa 70-316, His) | Mouse | HEK293 Cells |
Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune system. Subsequently, it has been shown that the RANKL-RANK ... | |||
TMPY-03506 | VILIP1 Protein, Human, Recombinant | Human | E. coli |
VILIP-1, also known as VSNL1, is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intracellular signaling pathways of the central nervou... | |||
TMPK-00717 | RANKL/TNFSF11/CD254 Protein, Human, Recombinant (His & Flag) | Human | HEK293 Cells |
Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune system. Subsequently, it has been shown that the RANKL-RANK ... | |||
TMPK-00279 | RGMA Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Repulsive guidance molecule (RGM) is a glycosylphosphatidylinositol (GPI)-anchored glycoprotein that has diverse functions in the developing and pathological central nervous system (CNS). The binding of RGM to its recept... | |||
TMPH-02864 | Wnt1 Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Ligand for members of the frizzled family of seven transmembrane receptors. Acts in the canonical Wnt signaling pathway by promoting beta-catenin-dependent transcriptional activation. In some developmental processes, is ... | |||
TMPK-00577 | ROR2 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, including bone and cartilage formation, as well as for the deve... | |||
TMPK-00579 | ROR2 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, including bone and cartilage formation, as well as for the deve... | |||
TMPK-00716 | RANKL/TNFSF11/CD254 Protein, Human, Recombinant (aa 63-244) | Human | HEK293 Cells |
Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune system. Subsequently, it has been shown that the RANKL-RANK ... | |||
TMPK-00278 | RGMA Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Repulsive guidance molecule (RGM) is a glycosylphosphatidylinositol (GPI)-anchored glycoprotein that has diverse functions in the developing and pathological central nervous system (CNS). The binding of RGM to its recept... | |||
TMPJ-01048 | VSNL1 Protein, Human, Recombinant (His) | Human | E. coli |
Visinin-Like Protein 1 (VILIP) is a a member of the Visinin/Recoverin subfamily of neuronal calcium sensor proteins. VILIP is strongly expressed in the Granule Cells of the Cerebellum where it associates with membranes i... | |||
TMPK-00566 | ROR2 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, including bone and cartilage formation, as well as for the deve... | |||
TMPK-00578 | ROR2 Protein, Human, Recombinant (aa 34-403, His & Avi), Biotinylated | Human | HEK293 Cells |
ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, including bone and cartilage formation, as well as for the deve... | |||
TMPJ-00395 | SEMA4D Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
SEMA4D is a member of the semaphorin family,contains one Ig-like C2-type domain, one PSI domain and one Sema domain. SEMA4D is strongly expressed in lymphoid tissues, especially in the thymus, as well as in the nervous t... | |||
TMPJ-00587 | NRCAM Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Neuronal cell adhesion molecule(NRCAM) is a single-pass type I membrane protein ,containing 5 fibronectin type-III domains and 6 Ig-like C2-type (immunoglobulin-like) domains.It belongs to the immunoglobulin superfamily.... | |||
TMPJ-00983 | ARRB1 Protein, Human, Recombinant (His) | Human | E. coli |
β-Arrestin-1 (ARRB1) is a cytoplasmic protein that belongs to the arrestin family. ARRB1 is expressed at high levels in peripheral blood leukocytes and the central nervous system. ARRB1 regulates agonist-mediated G-prote... | |||
TMPJ-00827 | Tau-D Protein, Human, Recombinant (His) | Human | E. coli |
Microtubule-Associated Protein TAU is abundantly expressed in neurons of the central nervous system and less commonly expressed elsewhere, but is also expressed at very low levels in CNS astrocytes and oligodendrocytes. ... | |||
TMPY-01563 | PMP2 Protein, Human, Recombinant (His) | Human | E. coli |
Myelin P2 protein, also known as PMP2, is a cytosolic protein found primarily in peripheral nerves. It Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. PMP2 is a small, basic, and cytoplasmic... | |||
TMPH-02321 | GLI1 Protein, Human, Recombinant (His) | Human | E. coli |
Acts as a transcriptional activator. Binds to the DNA consensus sequence 5'-GACCACCCA-3'. Regulates the transcription of specific genes during normal development. Plays a role in craniofacial development and digital deve... | |||
TMPJ-00701 | Carbonic Anhydrase 11 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Carbonic Anhydrase-Related Protein 11 (CA11) is a secreted protein member of the α-carbonic anhydrase family. Carbonic Anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of ... | |||
TMPJ-01398 | ITM2B Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Integral Membrane Protein 2B (ITM2B) is expressed in the Golgi and on the cell surface. ITM2B forms homodimer through disulfide-linked interaction with SPPL2A, SPPL2B and APP. ITM2B is expressed in brain and the other ti... | |||
TMPY-01118 | SLC27A4/FATP4 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
SLC27A4/ATG4B complex might act as a new potential therapeutic target of lung tumor chemotherapy. The solute carrier 27A (SLC27A) gene family encodes fatty acid transport proteins (FATPs) and includes 6 members. Autism s... | |||
TMPJ-00828 | Tau-F Protein, Human, Recombinant | Human | E. coli |
Tau proteins are proteins which contain four Tau/MAP repeats. They promote microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. They are abundant in neurons... | |||
TMPY-03175 | Claudin-11 Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
Claudin-11, also known as CLDN11, belongs to the group of claudins. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands function as a physical barrier to prevent solut... | |||
TMPJ-01125 | PEA15 Protein, Human, Recombinant | Human | E. coli |
Astrocyticphosphoprotein PEA-15 (PEA15) is a death effector domain (DED)-containing protein. PEA15 is mainly expressed in the central nervous system, principally in astrocytes. Increased PEA15 levels affect tumorigenesis... | |||
TMPJ-00302 | Serpin F2 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Alpha-2-antiplasmin, also called Serpin F2, is a serine protease inhibitor (serpin) responsible for inactivating plasmin, and an important enzyme participates in fibrinolysis and degradation of other proteins. In liver c... | |||
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