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Search Results for " central nervous system "

ターゲット

219

阻害剤

16

天然化合物

69

リコンビナントタンパク質

7

ライブラリー

カタログ番号 製品名 別名 ターゲット
TQ0091 LY2795050 Opioid Receptor
LY2795050 is a novel specific κ-Opioid Receptor antagonist (IC50: 0.72 nM).
T16849 SB-222200 Neurokinin receptor
SB-222200 is a selective, reversible, and competitive antagonist of the human NK-3 receptor(Ki=4.4 nM).
T6579 Medetomidine hydrochloride MPV785,Medetomidine HCl,Domitor Adrenergic Receptor
Medetomidine hydrochloride (MPV785) is a selective α2-adrenoceptor agonist, with Ki of 1.08 nM, exhibts 1620-fold selectivity over α1-adrenoceptor.
T28352 PDE9-IN-(S)-C33 (S)-C33 PDE
PDE9-IN-(S)-C33 ((S)-C33) is a potent and selective inhibitor of PDE9 (IC50 = 11 nM). PDE9-IN-(S)-C33 can be used for central nervous system diseases and diabetes research.
T19333 Gadoteridol ProHance,SQ-32692,Gd-HP-DO3A Others
Gadoteridol (Gd-HP-DO3A) is a gadolinium-based MRI contrast agent that can be used for central nervous system imaging.
T23008L MMPIP hydrochloride MMPIP hydrochloride (479077-02-6 Free base) GluR
MMPIP hydrochloride is a selective antagonist of allosteric mGluR7. MMPIP hydrochloride can be used in research on the roles of mGluR7 on central nervous system functions.
T0370 Pheniramine maleate Daneral,Inhiston,Trimetose 5-HT Receptor , Histamine Receptor
Pheniramine maleate (Trimetose), an alkylamine derivative with antihistaminic and vasodilatory properties, binds to histamine H1 receptors, thereby inhibiting phospholipase A2 and production of the endothelium-derived re...
T68079 Gedocarnil ZK 113315,SH 530 Others
Gedocarnil(ZK 113315) may be used to study diseases of the central nervous system.
T37089 Iclepertin BI-425809 GlyT
Iclepertin (BI-425809) is an orally active and selective inhibitor of glycine transporter protein 1 (GlyT1).Iclepertin is used for the treatment of central nervous system disorders such as Alzheimer;s disease. Iclepertin...
T35009 Vadocaine Vadocaina,Vadocainum Others
Vadocaine (Vadocaina) is a novel analgesic compound for local anaesthesia and can be used to study the central nervous system and cardiovascular system.
T27795 Landipirdine RO 5025181,RO5025181,SYN-120,SYN120,RO-5025181,SYN 120 5-HT Receptor
Landipirdine (RO-5025181) is a selective 5-HT6R antagonist for the study of central nervous system disorders such as dementia.
T7065 Tizanidine Adrenergic Receptor
Tizanidine, an α2-adrenergic receptor agonist, suppresses the release of neurotransmitters from central nervous system (CNS) noradrenergic neurons.
T10881 CPPHA GluR
CPPHA, a positive allosteric modulator of glutamate receptors mGluR5 and mGluR1, is commonly used in development for central nervous system diseases.
T10905 CXCR2-IN-1 CXCR
CXCR2-IN-1 has a pIC50 of 9.3 and is a CXCR2 antagonist of the central nervous system penetration agent.
T6618 Orphenadrine Citrate Flexon,Flexoject,Banflex AChR , iGluR
Orphenadrine Citrate (Flexon) is a skeletal muscle relaxant, it acts in the central nervous system to produce its muscle relaxant effects.
T27683 JNJ-42253432 P2X Receptor
JNJ-42253432 is an oral active P2X7 antagonist capable of penetrating the central nervous system with a pKi value of 9.1 for rat and 7.9 for human P2X7 channels.
T7118 Dimethocaine Larocaine Others , Dopamine Receptor
Dimethocaine (Larocaine) is a local anesthetic which also effects on the central nervous system acting as dopamine-reuptake-inhibitor.
T0702 Gabapentin Neurontin,Gabapentine,Aclonium Calcium Channel , GABA Receptor
Gabapentin (Neurontin) is an Anti-epileptic Agent. The physiologic effect of gabapentin is by means of Decreased Central Nervous System Disorganized Electrical Activity.
T5422 CID 1375606 CID-1375606,CID1375606 Others
CID 1375606 is a surrogate agonist of orphan G protein-coupled receptor GPR27. characterized by a high level of conservation among vertebrates and a predominant expression in the central nervous system.
T7433 2-Phenylethylamine hydrochloride &beta,-Phenylethylamine hydrochloride,benzeneethanamine hydrochloride,&beta,-aminoethylbenzene hydrochloride Others
2-Phenylethylamine hydrochloride (benzeneethanamine hydrochloride) acts as neuromodulator in the central nervous system. It stimulates the release of norepinephrine and dopamine and is metabolized by monoamine oxidases a...
T3659 Zorifertinib AZD3759 EGFR
Zorifertinib (AZD3759) is an orally active, effective and central nervous system-penetrant EGFR inhibitor. The IC50 values were 0.2, 0.3 and 0.2 nM for EGFR L858R mutant, TK wild-type, and Exon 19Del enzymes, respectivel...
T1946 Felbamate W-554,ADD-03055 NMDAR , iGluR
Felbamate (W-554) is an Anti-epileptic Agent. The physiologic effect of felbamate is by means of Decreased Central Nervous System Disorganized Electrical Activity.
T6649 (S)-(+)-Rolipram (S)-Rolipram,(+)-Rolipram,S- (+)-Rolipram Apoptosis , PDE
(S)-(+)-Rolipram ((+)-Rolipram) inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer.
T50063 (2-methyl-2,3-dihydro-1H-inden-2-yl)methanamine hydrochloride Others
(2-methyl-2,3-dihydro-1H-inden-2-yl)methanamine hydrochloride is a cyclic amine that is structurally related to amphetamine and has been shown to have significant effects on the central nervous system.
T32737 Liafensine BMS820836,BMS 820836,DB104,BMS-820836 Dopamine Receptor , 5-HT Receptor , Norepinephrine
Liafensine(BMS-820836) is a novel and selective triple monoamine reuptake inhibitor with inhibitory effects on the reuptake of serotonin, norepinephrine, and dopamine for the study of major depressive disorder and centra...
T2196 Fipronil Fluocyanobenpyrazole,Termidor P450 , GluCls , GABA Receptor
Fipronil (Fluocyanobenpyrazole) is a broad-use insecticide that belongs to the phenylpyrazole chemical family. Fipronil is a broad-spectrum insecticide that disrupts the insect central nervous system by blocking GABA-gat...
T6445 Cilomilast SB-207499,Ariflo PDE
Cilomilast (SB-207499) is a potent PDE4 inhibitor with IC50 of about 110 nM, has anti-inflammatory activity and low central nervous system activity. Phase 3.
T1097 Loratadine SCH 29851,Loratidine Influenza Virus , Histamine Receptor
Loratadine (SCH 29851) is a second-generation histamine H1 receptor antagonist used in the treatment of allergic rhinitis and urticaria. Unlike most classical antihistamines (HISTAMINE H1 ANTAGONISTS) it lacks central ne...
T2116 AEE788 NVP-AEE 788 Apoptosis , EGFR , c-Fms , FLT , Bcr-Abl
AEE788 (NVP-AEE 788) has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors.
TP1442 Neuromedin B Endogenous Metabolite
Neuromedin B (NMB) is one of the bombesin (BN)-related peptides in mammals. It was originally purified from pig spinal cords, and it has been shown to be present in central nervous system as well as in gastrointestinal t...
T0440 Oxcarbazepine GP 47680 Apoptosis , Sodium Channel
Oxcarbazepine (GP 47680) is an Anti-epileptic Agent. The physiologic effect of oxcarbazepine is by means of Decreased Central Nervous System Disorganized Electrical Activity.
T2407 Tiagabine TGB,NO050328,Gabitril,NO328 GABA Receptor
Tiagabine (NO050328) is an Anti-epileptic Agent. The physiologic effect of tiagabine is by means of Decreased Central Nervous System Disorganized Electrical Activity.
T13423 (1R,2R)-2-PCCA hydrochloride (1R,2R)-2-PCCA(hydrochloride) Others
(1R,2R)-2-PCCA hydrochloride is a potent, selective, and blood-brain-barrier-crossing GPR88 receptor agonist with an EC50 value of 1140 n in striatal membranes of WT mice.(1R,2R)-2-PCCA hydrochloride can be used to study...
T14345 Atropine methyl bromide Methylatropine bromide AChR
Atropine methyl bromide (Methylatropine bromide) is a quaternary ammonium salt of atropine, characterized as a muscarinic receptor (mAChR) antagonist. It functions as a mydriatic to dilate the pupil during ophthalmic exa...
T0680 Lamotrigine LTG,BW430C 5-HT Receptor , Sodium Channel , Autophagy
Lamotrigine (BW430C) is an Anti-epileptic Agent and Mood Stabilizer. The physiologic effect of lamotrigine is by means of Decreased Central Nervous System Disorganized Electrical Activity.
T9687 MAGL-IN-4 His121 ARG57 Lipase
MAGL-IN-4 (His121 ARG57) is one of the monoacylglycerol lipase (MAGL) inhibitors in central nervous system-related diseases.
T60712 MAO-B-IN-17 MAO
MAO-B-IN-17 is a selective and potent monoamine oxidase B (MAO-B) inhibitor (IC50: 5.08 μM) for the study of central nervous system disorders like Parkinson's.
T19940 Sulfoxaflor GF 2372,GF 2032,XDE 208 AChR
Sulfoxaflor (GF 2032), an agonist of nAChR1 and nAChR2 subtypes, is a systemic insecticide that acts on the central nervous system of insects. Sulfoxaflor is used for the control of sap-feeding insects such as Nilaparvat...
T30686 Cafedrine l-Cafedrine,Cafedrin Others
Cafedrine (Cafedrin) is found in tea and coffee and has a central nervous system stimulant effect.Cafedrine is often used in fixed 20:1 combination with cortisone in the study of acute hypotension.Cefetamet sodium (Cefet...
T23016 MRS1220 MRS 1220 Adenosine Receptor
MRS1220, a selective and potent antagonist for the human A3 adenosine receptor (hA3AR) with a dissociation constant (Ki) of 0.59 nM, exhibits therapeutic promise for central nervous system disease research. It effectivel...
T2191 Tacrine hydrochloride (hydrate) Tacrine,Tacrine hydrochloride hydrate,Tetrahydroaminacrine,Tetrahydroaminoacridine AChR , AChE
Tacrine hydrochloride hydrate (Tetrahydroaminacrine) is a cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and i...
T77731 ERK5-IN-6 ERK
ERK5-IN-6 is a potent inhibitor of ERK5 kinase.ERK5-IN-6 exhibits antiproliferative activity, anticonvulsant activity, and antitumor activity, and can be used in the study of central nervous system-related disorders.
T4249 AZD3759 hydrochloride EGFR
AZD3759 (hydrochloride) is an effective, orally active and central nervous system-penetrant EGFR inhibitor. At Km ATP concentrations, the IC50s are 0.2/0.3/0.2 nM for EGFR (L858R)/EGFR (wt)/EGFR (exon 19Del).
TP1083L Neuromedin U (rat) acetate Others
Neuromedin U, rat acetate is a 23-amino acid brain-gut peptide. Neuromedin U (NMU), through its cognate receptor NMUR2 in the central nervous system, regulates several important physiological functions, including energy ...
T1628 Rivastigmine tartrate SDZ-ENA 713,ENA 713 AChR , AChE
Rivastigmine tartrate (SDZ-ENA 713) is a carbamate-derived reversible CHOLINESTERASE INHIBITOR that is selective for the CENTRAL NERVOUS SYSTEM and is used for the treatment of DEMENTIA in ALZHEIMER DISEASE and PARKINSON...
T1790 Fosaprepitant dimeglumine L785298,MK-0517,Fosaprepitant dimeglumine salt Neurokinin receptor
Fosaprepitant dimeglumine (MK-0517) is the dimeglumine salt form of fosaprepitant, the water-soluble, N-phosphorylated prodrug of aprepitant, with antiemetic activity. Upon intravenous administration and rapid conversion...
T23097 O-1602 O1602,O 1602 Cannabinoid Receptor , Calcium Channel
O-1602 is a novel GPR55 agonist, an atypical cannabinoid associated with the central nervous system and obesity, and is a candidate compound for the treatment of cystitis.O-1602 promotes hepatic steatosis through GPR55 a...
T26778 Besipirdine HP 749 free base,P-867493,P867493,HP 749,HP749,P 867493 Sodium Channel , Adrenergic Receptor
Besipirdine (HP 749 free base) is a non-receptor-dependent cholinomimetic compound with alpha-adrenergic and cardiovascular activities.Besipirdine inhibits voltage-dependent sodium-potassium channels and inhibits biogeni...
T16115 MLi-2 LRRK2
MLi-2 is a structurally novel, highly potent, and selective LRRK2 kinase inhibitor with central nervous system activity. MLi-2 exhibits exceptional potency in a purified LRRK2 kinase assay in vitro (IC50 = 0.76 nM), a ce...
T2156 WP1066 Apoptosis , JAK , STAT
WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells; shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3. WP1066 has been used in trials studying the treatment of Melanoma, Bra...

Compounds

LY2795050
TQ0091
Synonym:
Target: Opioid Receptor
SB-222200
T16849
Synonym:
Target: Neurokinin receptor
Medetomidine hydrochloride
T6579
Synonym: MPV785,Medetomidine HCl,Domitor
Target: Adrenergic Receptor
PDE9-IN-(S)-C33
T28352
Synonym: (S)-C33
Target: PDE
Gadoteridol
T19333
Synonym: ProHance,SQ-32692,Gd-HP-DO3A
Target: Others
MMPIP hydrochloride
T23008L
Synonym: MMPIP hydrochloride (479077-02-6 Free base)
Target: GluR
Pheniramine maleate
T0370
Synonym: Daneral,Inhiston,Trimetose
Target: 5-HT Receptor, Histamine Receptor
Gedocarnil
T68079
Synonym: ZK 113315,SH 530
Target: Others
Iclepertin
T37089
Synonym: BI-425809
Target: GlyT
Vadocaine
T35009
Synonym: Vadocaina,Vadocainum
Target: Others
Landipirdine
T27795
Synonym: RO 5025181,RO5025181,SYN-120,SYN120,RO-5025181,SYN 120
Target: 5-HT Receptor
Tizanidine
T7065
Synonym:
Target: Adrenergic Receptor
CPPHA
T10881
Synonym:
Target: GluR
CXCR2-IN-1
T10905
Synonym:
Target: CXCR
Orphenadrine Citrate
T6618
Synonym: Flexon,Flexoject,Banflex
Target: AChR, iGluR
JNJ-42253432
T27683
Synonym:
Target: P2X Receptor
Dimethocaine
T7118
Synonym: Larocaine
Target: Others, Dopamine Receptor
Gabapentin
T0702
Synonym: Neurontin,Gabapentine,Aclonium
Target: Calcium Channel, GABA Receptor
CID 1375606
T5422
Synonym: CID-1375606,CID1375606
Target: Others
2-Phenylethylamine hydrochloride
T7433
Synonym: &beta,-Phenylethylamine hydrochloride,benzeneethanamine hydrochloride,&beta,-aminoethylbenzene hydrochloride
Target: Others
Zorifertinib
T3659
Synonym: AZD3759
Target: EGFR
Felbamate
T1946
Synonym: W-554,ADD-03055
Target: NMDAR, iGluR
(S)-(+)-Rolipram
T6649
Synonym: (S)-Rolipram,(+)-Rolipram,S- (+)-Rolipram
Target: Apoptosis, PDE
(2-methyl-2,3-dihydro-1H-inden-2-yl)methanamine hydrochloride
T50063
Synonym:
Target: Others
Liafensine
T32737
Synonym: BMS820836,BMS 820836,DB104,BMS-820836
Target: Dopamine Receptor, 5-HT Receptor, Norepinephrine
Fipronil
T2196
Synonym: Fluocyanobenpyrazole,Termidor
Target: P450, GluCls, GABA Receptor
Cilomilast
T6445
Synonym: SB-207499,Ariflo
Target: PDE
Loratadine
T1097
Synonym: SCH 29851,Loratidine
Target: Influenza Virus, Histamine Receptor
AEE788
T2116
Synonym: NVP-AEE 788
Target: Apoptosis, EGFR, c-Fms, FLT, Bcr-Abl
Neuromedin B
TP1442
Synonym:
Target: Endogenous Metabolite
Oxcarbazepine
T0440
Synonym: GP 47680
Target: Apoptosis, Sodium Channel
Tiagabine
T2407
Synonym: TGB,NO050328,Gabitril,NO328
Target: GABA Receptor
(1R,2R)-2-PCCA hydrochloride
T13423
Synonym: (1R,2R)-2-PCCA(hydrochloride)
Target: Others
Atropine methyl bromide
T14345
Synonym: Methylatropine bromide
Target: AChR
Lamotrigine
T0680
Synonym: LTG,BW430C
Target: 5-HT Receptor, Sodium Channel, Autophagy
MAGL-IN-4
T9687
Synonym: His121 ARG57
Target: Lipase
MAO-B-IN-17
T60712
Synonym:
Target: MAO
Sulfoxaflor
T19940
Synonym: GF 2372,GF 2032,XDE 208
Target: AChR
Cafedrine
T30686
Synonym: l-Cafedrine,Cafedrin
Target: Others
MRS1220
T23016
Synonym: MRS 1220
Target: Adenosine Receptor
Tacrine hydrochloride (hydrate)
T2191
Synonym: Tacrine,Tacrine hydrochloride hydrate,Tetrahydroaminacrine,Tetrahydroaminoacridine
Target: AChR, AChE
ERK5-IN-6
T77731
Synonym:
Target: ERK
AZD3759 hydrochloride
T4249
Synonym:
Target: EGFR
Neuromedin U (rat) acetate
TP1083L
Synonym:
Target: Others
Rivastigmine tartrate
T1628
Synonym: SDZ-ENA 713,ENA 713
Target: AChR, AChE
Fosaprepitant dimeglumine
T1790
Synonym: L785298,MK-0517,Fosaprepitant dimeglumine salt
Target: Neurokinin receptor
O-1602
T23097
Synonym: O1602,O 1602
Target: Cannabinoid Receptor, Calcium Channel
Besipirdine
T26778
Synonym: HP 749 free base,P-867493,P867493,HP 749,HP749,P 867493
Target: Sodium Channel, Adrenergic Receptor
MLi-2
T16115
Synonym:
Target: LRRK2
WP1066
T2156
Synonym:
Target: Apoptosis, JAK, STAT
1 2 3 4 5
カタログ番号 製品名 別名 ターゲット
T2S1464 Thiocolchicoside Thiocolchicine 2-glucoside analog,Coltramyl Others , GABA Receptor
Thiocolchicoside (Thiocolchicine 2-glucoside analog) (Muscoril, Myoril, Neoflax) is a muscle relaxant with anti-inflammatory and analgesic effects. It acts as a competitive GABAA receptor antagonist and also glycine rece...
T0508 γ-Aminobutyric acid Gamma-aminobutyric acid,4-Aminobutyric acid,GABA,4-Aminobutanoic acid,Piperidic acid GABA Receptor , Endogenous Metabolite
γ-Aminobutyric acid (4-Aminobutyric acid) is the most common inhibitory neurotransmitter in the central nervous system.
T1396 Bemegride Bemegrid,3-Ethyl-3-methylglutarimide,Agipnon GABA Receptor
Bemegride (3-Ethyl-3-methylglutarimide), a central nervous system stimulant, serves as an antidote for barbiturate poisoning.
T6751 Acetylcholine iodide Acetylcolina Others
Acetylcholine iodide (Acetylcolina) is a neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the cent...
T14046 Anandamide (5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide Cannabinoid Receptor , Endogenous Metabolite
Anandamide ((5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide), an immune modulator, acts via not only cannabinoid receptors (CB1 and CB2) but also other targets (e.g., GPR18/GPR55) in the central nervous sy...
T1083 Theophylline Theo-24,1,3-Dimethylxanthine Endogenous Metabolite , HDAC , PDE , Adenosine Receptor , Autophagy
Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3...
TN2322 Yangambin Calcium Channel , PAFR
Yangambin is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF); it has hypotensive effect, which is probably due to a peripheral vasodilatation that involves, at least, the inhibiti...
T4A2458 Resibufogenin Bufogenin,Recibufogenin Others
1. Resibufogenin (Bufogenin) is a cytotoxic steroid isolated from the Chinese drug ChanSu. 2. Resibufogenin can inhibit rectifier potassium current ( I K ) and transient potassium current ( I A ), it has pathological eff...
TN1516 Cnidicin NOS , NO Synthase
Cnidicin has anti-allergic and anti-inflammatory activity, it inhibits the degranulation of mast cell and the NO generation in RAW 264.7 cells(IC50 value, 7.5 microM). Cnidicin exhibits a significant inhibition on the pr...
T6S1049 Wilforine ATPase
Wilforine is a sesquiterpene pyridine alkaloid; important bioactive compound in T. wilfordii plants, and is effective in treating idiopathic pulmonary fibrosis. Wilforine has anti-inflammatory effect, which might be medi...
T15248 Estetrol Donesta Estrogen Receptor/ERR , Endogenous Metabolite
Estetrol(Donesta) is an orally available, selective modulator of the estrogen receptor, a naturally occurring estrogen synthesized by the human fetal liver during pregnancy.Estetrol has effects on the endometrium or cent...
T0848 L-DOPA Levodopa,3,4-Dihydroxyphenylalanine Dopamine Receptor , Endogenous Metabolite
L-DOPA (Levodopa) is an amino acid precursor of dopamine with antiparkinsonian properties. Levodopa is a prodrug that is converted to dopamine by DOPA decarboxylase and can cross the blood-brain barrier. When in the brai...
TN2240 Strictosidinic acid Others
Strictosidinic acid has an antiradical action against DPPH, it has a promising effect in the central nervous system.
TMA0805 Lupanine ATPase , Potassium Channel , Calcium Channel
Lupanine has a weak sedative effect on the central nervous system, interaction with specific drugs used for treatment of the CNS and for analgesic activity. Lupanine improves glucose homeostasis by influencing KATP-chann...
T35577 Phosphatidylserines (bovine)
Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. It is anionic and found mainly on th...
T14011 2-Arachidonoylglycerol Cannabinoid Receptor , Endogenous Metabolite

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-05054 Notch 4 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
NOTCH4 (Notch Receptor 4) is a Protein Coding gene. Notch4 belongs to a family of transmembrane receptors that play an important role in vascular development and maintenance. The NOTCH4 gene is located at 6p21.3 and is i...
TMPY-03425 Tau Protein, Human, Recombinant (His) Human E. coli
MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are...
TMPY-02525 RGMA Protein, Human, Recombinant (His) Human HEK293 Cells
RGMa, also known as RGM domain family, member A, belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein th...
TMPJ-00651 CD155/PVR Protein, Human, Recombinant (aa 21-343, His) Human HEK293 Cells
Poliovirus Receptor (PVR) is a 70 kDa type I transmembrane single-span glycoprotein that belongs to the nectin-like (Necl) family and was originally identified based on its ability to mediate the cell attachment and entr...
TMPJ-00562 PDGF-BB Protein, Mouse, Recombinant (His) Mouse E. coli
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (P...
TMPY-01442 DMBT1 Protein, Human, Recombinant (His) Human HEK293 Cells
Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB d...
TMPJ-01065 Noggin/NOG Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Noggin is a secreted homodimeric glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). Mouse Noggin cDNA encodes a 232 amino acid (aa) residue precursor protein with 19 aa residue putative signal pept...
TMPY-01101 Coagulation factor X/F10 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
Coagulation factor X, also known as FX, F10, Eponym Stuart-Prower factor, and thrombokinase, is an enzyme of the coagulation cascade. It is one of the vitamin K-dependent serine proteases, and plays a crucial role in the...
TMPH-02489 ASCL2 Protein, Mouse, Recombinant (His & Myc) Mouse E. coli
AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. ASCL2 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression...
TMPH-01722 PLP1 Protein, Human, Recombinant (His) Human E. coli
This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin. PLP1 Protein, Human, Recombinant (His) is expressed i...
TMPH-02653 FGF-20 Protein, Mouse, Recombinant Mouse E. coli
Neurotrophic factor that regulates central nervous development and function. FGF-20 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 23.6 kDa and the accession numb...
TMPH-02673 GFAP Protein, Mouse, Recombinant (His & SUMO) Mouse E. coli
GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
TMPY-00561 Neurotensin Protein, Human, Recombinant (hFc) Human HEK293 Cells
NTS (Neurotensin) is a Protein Coding gene. This gene encodes a common precursor for two peptides, neuromedin N and neurotensin. NTS is a neuropeptide distributed in the central nervous and digestive systems. It belongs ...
TMPH-02674 GFAP Protein, Mouse, Recombinant Mouse Baculovirus Insect Cells
GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
TMPH-01504 HAPLN2 Protein, Human, Recombinant (His) Human E. coli
Mediates a firm binding of versican V2 to hyaluronic acid. May play a pivotal role in the formation of the hyaluronan-associated matrix in the central nervous system (CNS) which facilitates neuronal conduction and genera...
TMPY-00286 Neuropeptide Y Protein, Human, Recombinant (hFc) Human HEK293 Cells
NPY (Neuropeptide Y) is a Protein Coding gene. This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress ...
TMPJ-00846 GFAP Protein, Human, Recombinant (His) Human E. coli
Glial Fibrillary Acidic Protein (GFAP) is an intermediate filament (IF) protein which belongs to the intermediate filament family. GFAP is expressed in numerous cell types of the central nervous system (CNS), ependymal c...
TMPK-01062 RGMC Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
RGM gene family ('Repulsive Axonal Guidance molecules' A, B and C),both RGM A and B are mostly expressed in central nervous system, while RGM C is exclusively expressed in all striated muscle and in the myocardium. RGM A...
TMPH-03292 FGF-20 Protein, Rat, Recombinant (His & Myc) Rat E. coli
Neurotrophic factor that regulates central nervous development and function. May play an important role in dopaminergic neurons in the substantia nigra. FGF-20 Protein, Rat, Recombinant (His & Myc) is expressed in E. col...
TMPH-03756 Wint7b Protein, Human, Recombinant (His & Myc & SUMO) Human E. coli
Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta-catenin signaling pathway. Required for normal fusion of the chorion and the allantois during placenta d...
TMPH-02861 Wnt7b Protein, Mouse, Recombinant (His & Myc & SUMO) Mouse E. coli
Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta-catenin signaling pathway. Required for normal fusion of the chorion and the allantois during placenta d...
TMPJ-00295 NgR Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Nogo Receptor (NgR) is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the Nogo recptor family. Human NgR is predominantly expressed in neurons and their axons in the central nervous systems. As a recept...
TMPK-00861 A2AR Protein-VLP, Human, Recombinant Human HEK293 Cells
Adenosine is a neuromodulator in the adult central nervous system. Membrane-bound receptors for adenosine have been identified and cDNAs for A1, A2a, A2b, and A3 adenosine receptor subtypes have been cloned recently.Expr...
TMPJ-00945 HPCAL1 Protein, Human, Recombinant (His) Human E. coli
Hippocalcin-Like Protein 1 (HPCAL1) is a neuron-specific calcium-binding member of the recoverin family which found in the retina and brain. HPCAL1 contains four EF-hand domains and it is highly similar to human hippocal...
TMPY-01120 VPAC2 Protein, Human, Recombinant (mFc) Human HEK293 Cells
VIP and PACAP receptor 2, or VIPR2 encodes the VPAC2 receptor, which binds both VIP and PACAP. VPAC2 is expressed throughout the central nervous system and the periphery. Mutations in the VIPR2 homolog in the mouse cause...
TMPK-00591 RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (aa 70-316, His) Mouse HEK293 Cells
Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune system. Subsequently, it has been shown that the RANKL-RANK ...
TMPY-03506 VILIP1 Protein, Human, Recombinant Human E. coli
VILIP-1, also known as VSNL1, is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intracellular signaling pathways of the central nervou...
TMPK-00717 RANKL/TNFSF11/CD254 Protein, Human, Recombinant (His & Flag) Human HEK293 Cells
Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune system. Subsequently, it has been shown that the RANKL-RANK ...
TMPK-00279 RGMA Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
Repulsive guidance molecule (RGM) is a glycosylphosphatidylinositol (GPI)-anchored glycoprotein that has diverse functions in the developing and pathological central nervous system (CNS). The binding of RGM to its recept...
TMPH-02864 Wnt1 Protein, Mouse, Recombinant (His & Myc) Mouse E. coli
Ligand for members of the frizzled family of seven transmembrane receptors. Acts in the canonical Wnt signaling pathway by promoting beta-catenin-dependent transcriptional activation. In some developmental processes, is ...
TMPK-00577 ROR2 Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, including bone and cartilage formation, as well as for the deve...
TMPK-00579 ROR2 Protein, Human, Recombinant (hFc) Human HEK293 Cells
ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, including bone and cartilage formation, as well as for the deve...
TMPK-00716 RANKL/TNFSF11/CD254 Protein, Human, Recombinant (aa 63-244) Human HEK293 Cells
Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune system. Subsequently, it has been shown that the RANKL-RANK ...
TMPK-00278 RGMA Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
Repulsive guidance molecule (RGM) is a glycosylphosphatidylinositol (GPI)-anchored glycoprotein that has diverse functions in the developing and pathological central nervous system (CNS). The binding of RGM to its recept...
TMPJ-01048 VSNL1 Protein, Human, Recombinant (His) Human E. coli
Visinin-Like Protein 1 (VILIP) is a a member of the Visinin/Recoverin subfamily of neuronal calcium sensor proteins. VILIP is strongly expressed in the Granule Cells of the Cerebellum where it associates with membranes i...
TMPK-00566 ROR2 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, including bone and cartilage formation, as well as for the deve...
TMPK-00578 ROR2 Protein, Human, Recombinant (aa 34-403, His & Avi), Biotinylated Human HEK293 Cells
ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, including bone and cartilage formation, as well as for the deve...
TMPJ-00395 SEMA4D Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
SEMA4D is a member of the semaphorin family,contains one Ig-like C2-type domain, one PSI domain and one Sema domain. SEMA4D is strongly expressed in lymphoid tissues, especially in the thymus, as well as in the nervous t...
TMPJ-00587 NRCAM Protein, Human, Recombinant (hFc) Human HEK293 Cells
Neuronal cell adhesion molecule(NRCAM) is a single-pass type I membrane protein ,containing 5 fibronectin type-III domains and 6 Ig-like C2-type (immunoglobulin-like) domains.It belongs to the immunoglobulin superfamily....
TMPJ-00983 ARRB1 Protein, Human, Recombinant (His) Human E. coli
β-Arrestin-1 (ARRB1) is a cytoplasmic protein that belongs to the arrestin family. ARRB1 is expressed at high levels in peripheral blood leukocytes and the central nervous system. ARRB1 regulates agonist-mediated G-prote...
TMPJ-00827 Tau-D Protein, Human, Recombinant (His) Human E. coli
Microtubule-Associated Protein TAU is abundantly expressed in neurons of the central nervous system and less commonly expressed elsewhere, but is also expressed at very low levels in CNS astrocytes and oligodendrocytes. ...
TMPY-01563 PMP2 Protein, Human, Recombinant (His) Human E. coli
Myelin P2 protein, also known as PMP2, is a cytosolic protein found primarily in peripheral nerves. It Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. PMP2 is a small, basic, and cytoplasmic...
TMPH-02321 GLI1 Protein, Human, Recombinant (His) Human E. coli
Acts as a transcriptional activator. Binds to the DNA consensus sequence 5'-GACCACCCA-3'. Regulates the transcription of specific genes during normal development. Plays a role in craniofacial development and digital deve...
TMPJ-00701 Carbonic Anhydrase 11 Protein, Human, Recombinant (His) Human HEK293 Cells
Carbonic Anhydrase-Related Protein 11 (CA11) is a secreted protein member of the α-carbonic anhydrase family. Carbonic Anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of ...
TMPJ-01398 ITM2B Protein, Human, Recombinant (His) Human HEK293 Cells
Integral Membrane Protein 2B (ITM2B) is expressed in the Golgi and on the cell surface. ITM2B forms homodimer through disulfide-linked interaction with SPPL2A, SPPL2B and APP. ITM2B is expressed in brain and the other ti...
TMPY-01118 SLC27A4/FATP4 Protein, Human, Recombinant (His) Human HEK293 Cells
SLC27A4/ATG4B complex might act as a new potential therapeutic target of lung tumor chemotherapy. The solute carrier 27A (SLC27A) gene family encodes fatty acid transport proteins (FATPs) and includes 6 members. Autism s...
TMPJ-00828 Tau-F Protein, Human, Recombinant Human E. coli
Tau proteins are proteins which contain four Tau/MAP repeats. They promote microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. They are abundant in neurons...
TMPY-03175 Claudin-11 Protein, Human, Recombinant (mFc) Human HEK293 Cells
Claudin-11, also known as CLDN11, belongs to the group of claudins. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands function as a physical barrier to prevent solut...
TMPJ-01125 PEA15 Protein, Human, Recombinant Human E. coli
Astrocyticphosphoprotein PEA-15 (PEA15) is a death effector domain (DED)-containing protein. PEA15 is mainly expressed in the central nervous system, principally in astrocytes. Increased PEA15 levels affect tumorigenesis...
TMPJ-00302 Serpin F2 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Alpha-2-antiplasmin, also called Serpin F2, is a serine protease inhibitor (serpin) responsible for inactivating plasmin, and an important enzyme participates in fibrinolysis and degradation of other proteins. In liver c...
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Notch 4 Protein, Human, Recombinant (His)
TMPY-05054
Species: Human
Expression System: Baculovirus Insect Cells
Tau Protein, Human, Recombinant (His)
TMPY-03425
Species: Human
Expression System: E. coli
RGMA Protein, Human, Recombinant (His)
TMPY-02525
Species: Human
Expression System: HEK293 Cells
CD155/PVR Protein, Human, Recombinant (aa 21-343, His)
TMPJ-00651
Species: Human
Expression System: HEK293 Cells
PDGF-BB Protein, Mouse, Recombinant (His)
TMPJ-00562
Species: Mouse
Expression System: E. coli
DMBT1 Protein, Human, Recombinant (His)
TMPY-01442
Species: Human
Expression System: HEK293 Cells
Noggin/NOG Protein, Mouse, Recombinant (His)
TMPJ-01065
Species: Mouse
Expression System: HEK293 Cells
Coagulation factor X/F10 Protein, Human, Recombinant (His)
TMPY-01101
Species: Human
Expression System: Baculovirus Insect Cells
ASCL2 Protein, Mouse, Recombinant (His & Myc)
TMPH-02489
Species: Mouse
Expression System: E. coli
PLP1 Protein, Human, Recombinant (His)
TMPH-01722
Species: Human
Expression System: E. coli
FGF-20 Protein, Mouse, Recombinant
TMPH-02653
Species: Mouse
Expression System: E. coli
GFAP Protein, Mouse, Recombinant (His & SUMO)
TMPH-02673
Species: Mouse
Expression System: E. coli
Neurotensin Protein, Human, Recombinant (hFc)
TMPY-00561
Species: Human
Expression System: HEK293 Cells
GFAP Protein, Mouse, Recombinant
TMPH-02674
Species: Mouse
Expression System: Baculovirus Insect Cells
HAPLN2 Protein, Human, Recombinant (His)
TMPH-01504
Species: Human
Expression System: E. coli
Neuropeptide Y Protein, Human, Recombinant (hFc)
TMPY-00286
Species: Human
Expression System: HEK293 Cells
GFAP Protein, Human, Recombinant (His)
TMPJ-00846
Species: Human
Expression System: E. coli
RGMC Protein, Mouse, Recombinant (His)
TMPK-01062
Species: Mouse
Expression System: HEK293 Cells
FGF-20 Protein, Rat, Recombinant (His & Myc)
TMPH-03292
Species: Rat
Expression System: E. coli
Wint7b Protein, Human, Recombinant (His & Myc & SUMO)
TMPH-03756
Species: Human
Expression System: E. coli
Wnt7b Protein, Mouse, Recombinant (His & Myc & SUMO)
TMPH-02861
Species: Mouse
Expression System: E. coli
NgR Protein, Mouse, Recombinant (hFc)
TMPJ-00295
Species: Mouse
Expression System: HEK293 Cells
A2AR Protein-VLP, Human, Recombinant
TMPK-00861
Species: Human
Expression System: HEK293 Cells
HPCAL1 Protein, Human, Recombinant (His)
TMPJ-00945
Species: Human
Expression System: E. coli
VPAC2 Protein, Human, Recombinant (mFc)
TMPY-01120
Species: Human
Expression System: HEK293 Cells
RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (aa 70-316, His)
TMPK-00591
Species: Mouse
Expression System: HEK293 Cells
VILIP1 Protein, Human, Recombinant
TMPY-03506
Species: Human
Expression System: E. coli
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (His & Flag)
TMPK-00717
Species: Human
Expression System: HEK293 Cells
RGMA Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00279
Species: Human
Expression System: HEK293 Cells
Wnt1 Protein, Mouse, Recombinant (His & Myc)
TMPH-02864
Species: Mouse
Expression System: E. coli
ROR2 Protein, Human, Recombinant (His & Avi)
TMPK-00577
Species: Human
Expression System: HEK293 Cells
ROR2 Protein, Human, Recombinant (hFc)
TMPK-00579
Species: Human
Expression System: HEK293 Cells
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (aa 63-244)
TMPK-00716
Species: Human
Expression System: HEK293 Cells
RGMA Protein, Human, Recombinant (His & Avi)
TMPK-00278
Species: Human
Expression System: HEK293 Cells
VSNL1 Protein, Human, Recombinant (His)
TMPJ-01048
Species: Human
Expression System: E. coli
ROR2 Protein, Cynomolgus, Recombinant (His)
TMPK-00566
Species: Cynomolgus
Expression System: HEK293 Cells
ROR2 Protein, Human, Recombinant (aa 34-403, His & Avi), Biotinylated
TMPK-00578
Species: Human
Expression System: HEK293 Cells
SEMA4D Protein, Mouse, Recombinant (hFc)
TMPJ-00395
Species: Mouse
Expression System: HEK293 Cells
NRCAM Protein, Human, Recombinant (hFc)
TMPJ-00587
Species: Human
Expression System: HEK293 Cells
ARRB1 Protein, Human, Recombinant (His)
TMPJ-00983
Species: Human
Expression System: E. coli
Tau-D Protein, Human, Recombinant (His)
TMPJ-00827
Species: Human
Expression System: E. coli
PMP2 Protein, Human, Recombinant (His)
TMPY-01563
Species: Human
Expression System: E. coli
GLI1 Protein, Human, Recombinant (His)
TMPH-02321
Species: Human
Expression System: E. coli
Carbonic Anhydrase 11 Protein, Human, Recombinant (His)
TMPJ-00701
Species: Human
Expression System: HEK293 Cells
ITM2B Protein, Human, Recombinant (His)
TMPJ-01398
Species: Human
Expression System: HEK293 Cells
SLC27A4/FATP4 Protein, Human, Recombinant (His)
TMPY-01118
Species: Human
Expression System: HEK293 Cells
Tau-F Protein, Human, Recombinant
TMPJ-00828
Species: Human
Expression System: E. coli
Claudin-11 Protein, Human, Recombinant (mFc)
TMPY-03175
Species: Human
Expression System: HEK293 Cells
PEA15 Protein, Human, Recombinant
TMPJ-01125
Species: Human
Expression System: E. coli
Serpin F2 Protein, Mouse, Recombinant (hFc)
TMPJ-00302
Species: Mouse
Expression System: HEK293 Cells
カタログ番号 製品名
L2620 Anti-Neurodegenerative Disease Compound Library

2154 compounds
A unique collection of 2154 compounds related to neurodegenerative diseases can be used for HTS or HCS;
L7700 Neural Regeneration Compound Library

524 compounds
A unique collection of 149 neuroregeneration related compounds for high throughput and high content screening;
L2800 Serotonin Receptor-Targeted Compound Library

268 compounds
A unique collection of 268 compounds targeting serotonin receptors for high throughput screening and high content screening;
L3300 Histamine & Melatonin Receptor-Targeted Compound Library

153 compounds
A unique collection of 153 compounds targeting histaminergic receptor and melatonin receptor for high throughput screening (HTS) and high content screening (HCS) for new drugs;
L5900 CNS-Penetrant Compound Library

509 compounds
A unique collection of 509 CNS-Penetrant compounds for high throughput screening (HTS) and high content screening (HCS);
L4300 Wnt/Hedgehog/Notch Compound Library

237 compounds
A unique collection of 237 Wnt/Hedgehog/Notch signaling targeted compounds for high throughput and high content screening;
L2610 Neurotransmitter Receptor Compound Library

1513 compounds
A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening;